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Researched by Helena DeMaria-Williams

Formula IngredientHumectant, Solvent

2-Hexanediol

INCI: 1,2-Hexanediol

1,2-Hexanediol is a short-chain diol (two hydroxyl groups on a six-carbon chain) used in cosmetics as a humectant, solvent, and antimicrobial booster. It helps retain moisture in the skin and contributes a soft, pleasant skin feel. It is also widely used to enhance the efficacy of traditional preservatives, allowing formulators to reduce their concentration.

Category

Humectant, Solvent

Irritation Risk

Low

Skin Types

all skin types, oily, acne-prone, sensitive, combination, dry

What does this do in a formula?

moisturisation, skin conditioning, solvent for active ingredients, antimicrobial preservative boosting, improves skin feel, pigment dispersion in makeup

Is 2-Hexanediol safe? Key considerations

Can 2-Hexanediol cause irritation?

Low Risk

Well-tolerated at cosmetic concentrations (typically 0.5–2%). No EU CosIng Annex II or III restrictions apply. At higher concentrations it may cause mild transient irritation, but this is uncommon in standard formulations. Sensitisation potential is considered very low.

Does 2-Hexanediol increase sun sensitivity?

No Risk

1,2-Hexanediol does not increase photosensitivity. No sun protection precautions are needed based on its presence in a formulation.

Is 2-Hexanediol safe during pregnancy?

Caution

No specific reproductive or developmental toxicity concerns have been identified in cosmetic use databases. However, dedicated pregnancy safety studies are limited. At typical cosmetic concentrations (0.5–2%), systemic absorption is very low and risk is considered minimal. Consult a healthcare provider if concerned.

How does 2-Hexanediol work?

1,2-Hexanediol is a short-chain diol (two hydroxyl groups on a six-carbon chain) used in cosmetics as a humectant, solvent, and antimicrobial booster. It helps retain moisture in the skin and contributes a soft, pleasant skin feel. It is also widely used to enhance the efficacy of traditional preservatives, allowing formulators to reduce their concentration.