Researched by Helena DeMaria-Williams
Formula IngredientSkin-Soothing Agent4-T-Butylcyclohexanol
INCI: Cyclohexanol, 4-(1,1-Dimethylethyl)-
4-t-butylcyclohexanol is a synthetic fatty alcohol and TRPV1 (transient receptor potential vanilloid 1) receptor antagonist. It works by intercepting irritation signals — specifically the stinging and burning sensations triggered by environmental or chemical stimuli — before they reach sensory nerve receptors, thereby raising the skin's irritation tolerance threshold. Clinical studies show it can reduce stinging by up to 78% and burning by up to 80% within 3 minutes of application.
Category
Skin-Soothing Agent
Irritation Risk
Low
Skin Types
sensitive, reactive, rosacea-prone, irritated, combination, all skin types
What does this do in a formula?
reduces stinging and burning sensations, calms redness, soothes sensitive and reactive skin, reduces shaving-induced irritation, supports skin barrier function
Is 4-T-Butylcyclohexanol safe? Key considerations
Can 4-T-Butylcyclohexanol cause irritation?
Low RiskConsidered non-irritating; functions specifically as an anti-irritant. No formal EU Annex restrictions apply. Well tolerated in clinical trials involving sensitive skin and rosacea subjects.
Does 4-T-Butylcyclohexanol increase sun sensitivity?
No RiskNo known photosensitising effect. This ingredient does not increase UV sensitivity.
Is 4-T-Butylcyclohexanol safe during pregnancy?
CautionNo dedicated pregnancy safety studies exist for this ingredient. It is present in some products marketed as pregnancy-safe, but given the absence of formal reproductive toxicity data, a cautious approach is recommended. Consult a healthcare provider before use during pregnancy. (MANUAL REVIEW: limited pregnancy-specific data available)
How does 4-T-Butylcyclohexanol work?
4-t-butylcyclohexanol is a synthetic fatty alcohol and TRPV1 (transient receptor potential vanilloid 1) receptor antagonist. It works by intercepting irritation signals — specifically the stinging and burning sensations triggered by environmental or chemical stimuli — before they reach sensory nerve receptors, thereby raising the skin's irritation tolerance threshold. Clinical studies show it can reduce stinging by up to 78% and burning by up to 80% within 3 minutes of application.
Individuals with known allergy to fatty alcohols or this specific compound should review the considerations above before use.
Which products contain 4-T-Butylcyclohexanol?
Shop products that contain 4-T-Butylcyclohexanol
