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Researched by Helena DeMaria-Williams

Formula IngredientPeptide

Acetyl Tetrapeptide-2

INCI: Acetyl Tetrapeptide-2

Acetyl Tetrapeptide-2 is a four-amino-acid synthetic peptide created through acetylation of tetrapeptide-2. It mimics thymopoietin, a hormone produced by the thymus gland that declines with age. By compensating for the loss of thymic factors, it is claimed to stimulate the skin's immune defences and support skin regeneration. It is marketed under the trade name Thymulen 4.

Category

Peptide

Irritation Risk

Low

Skin Types

all skin types, mature, anti-ageing concerns, dull or fatigued skin

What does this do in a formula?

anti-ageing, skin immune defence support, skin regeneration, skin conditioning, firmness improvement

Is Acetyl Tetrapeptide-2 safe? Key considerations

Can Acetyl Tetrapeptide-2 cause irritation?

Low Risk

Acetyl tetrapeptide-2 is used at very low concentrations in cosmetic formulations and is well tolerated. No EU CosIng Annex II or III restrictions apply. Synthetic peptides are generally non-irritating.

Does Acetyl Tetrapeptide-2 increase sun sensitivity?

No Risk

Acetyl tetrapeptide-2 does not increase photosensitivity. No special sun protection measures are required beyond a standard daily SPF routine.

Is Acetyl Tetrapeptide-2 safe during pregnancy?

Caution

MANUAL REVIEW: No specific pregnancy safety data exists for topical acetyl tetrapeptide-2. As a synthetic peptide used at very low concentrations with minimal systemic absorption, it is unlikely to pose significant risk, but the absence of dedicated pregnancy safety studies warrants caution. Consult a healthcare provider if concerned.

How does Acetyl Tetrapeptide-2 work?

Acetyl Tetrapeptide-2 is a four-amino-acid synthetic peptide created through acetylation of tetrapeptide-2. It mimics thymopoietin, a hormone produced by the thymus gland that declines with age. By compensating for the loss of thymic factors, it is claimed to stimulate the skin's immune defences and support skin regeneration. It is marketed under the trade name Thymulen 4.

Which products contain Acetyl Tetrapeptide-2?

Shop products that contain Acetyl Tetrapeptide-2