Researched by Helena DeMaria-Williams
Formula IngredientPeptideINCI: Acetyl Tetrapeptide-2
Acetyl Tetrapeptide-2 is a four-amino-acid synthetic peptide created through acetylation of tetrapeptide-2. It mimics thymopoietin, a hormone produced by the thymus gland that declines with age. By compensating for the loss of thymic factors, it is claimed to stimulate the skin's immune defences and support skin regeneration. It is marketed under the trade name Thymulen 4.
Category
Peptide
Irritation Risk
Low
Skin Types
all skin types, mature, anti-ageing concerns, dull or fatigued skin
anti-ageing, skin immune defence support, skin regeneration, skin conditioning, firmness improvement
Acetyl tetrapeptide-2 is used at very low concentrations in cosmetic formulations and is well tolerated. No EU CosIng Annex II or III restrictions apply. Synthetic peptides are generally non-irritating.
Acetyl tetrapeptide-2 does not increase photosensitivity. No special sun protection measures are required beyond a standard daily SPF routine.
MANUAL REVIEW: No specific pregnancy safety data exists for topical acetyl tetrapeptide-2. As a synthetic peptide used at very low concentrations with minimal systemic absorption, it is unlikely to pose significant risk, but the absence of dedicated pregnancy safety studies warrants caution. Consult a healthcare provider if concerned.
Acetyl Tetrapeptide-2 is a four-amino-acid synthetic peptide created through acetylation of tetrapeptide-2. It mimics thymopoietin, a hormone produced by the thymus gland that declines with age. By compensating for the loss of thymic factors, it is claimed to stimulate the skin's immune defences and support skin regeneration. It is marketed under the trade name Thymulen 4.
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