Researched by Helena DeMaria-Williams
Formula IngredientPeptideINCI: Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-3 is a synthetic four-amino-acid peptide that is a key component of the trademarked Capixyl complex. It works by stimulating extracellular matrix proteins in the scalp, increasing type III collagen expression by up to 65% and laminin expression by up to 285%, which strengthens the hair follicle anchoring environment. It also inhibits 5-alpha-reductase, the enzyme responsible for converting testosterone to DHT, a key driver of androgenetic hair loss.
Category
Peptide
Irritation Risk
Low
Skin Types
thinning hair, androgenetic alopecia, hair loss concerns, all skin types
hair growth stimulation, hair loss reduction, DHT inhibition, collagen stimulation, scalp health, follicle strengthening
Peptides are generally well tolerated at cosmetic concentrations. No EU CosIng Annex II or III restrictions apply. No significant irritation reports at typical use levels.
Acetyl Tetrapeptide-3 does not increase photosensitivity. No additional sun protection is required beyond a standard daily SPF routine.
MANUAL REVIEW: Limited data on topical peptide safety during pregnancy. While systemic absorption is expected to be minimal, no specific pregnancy safety studies are available. Consult a healthcare provider.
Acetyl Tetrapeptide-3 is a synthetic four-amino-acid peptide that is a key component of the trademarked Capixyl complex. It works by stimulating extracellular matrix proteins in the scalp, increasing type III collagen expression by up to 65% and laminin expression by up to 285%, which strengthens the hair follicle anchoring environment. It also inhibits 5-alpha-reductase, the enzyme responsible for converting testosterone to DHT, a key driver of androgenetic hair loss.
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