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Researched by Helena DeMaria-Williams

Formula IngredientPeptide

Acetyl Tetrapeptide-3

INCI: Acetyl Tetrapeptide-3

Acetyl Tetrapeptide-3 is a synthetic four-amino-acid peptide that is a key component of the trademarked Capixyl complex. It works by stimulating extracellular matrix proteins in the scalp, increasing type III collagen expression by up to 65% and laminin expression by up to 285%, which strengthens the hair follicle anchoring environment. It also inhibits 5-alpha-reductase, the enzyme responsible for converting testosterone to DHT, a key driver of androgenetic hair loss.

Category

Peptide

Irritation Risk

Low

Skin Types

thinning hair, androgenetic alopecia, hair loss concerns, all skin types

What does this do in a formula?

hair growth stimulation, hair loss reduction, DHT inhibition, collagen stimulation, scalp health, follicle strengthening

Is Acetyl Tetrapeptide-3 safe? Key considerations

Can Acetyl Tetrapeptide-3 cause irritation?

Low Risk

Peptides are generally well tolerated at cosmetic concentrations. No EU CosIng Annex II or III restrictions apply. No significant irritation reports at typical use levels.

Does Acetyl Tetrapeptide-3 increase sun sensitivity?

No Risk

Acetyl Tetrapeptide-3 does not increase photosensitivity. No additional sun protection is required beyond a standard daily SPF routine.

Is Acetyl Tetrapeptide-3 safe during pregnancy?

Caution

MANUAL REVIEW: Limited data on topical peptide safety during pregnancy. While systemic absorption is expected to be minimal, no specific pregnancy safety studies are available. Consult a healthcare provider.

How does Acetyl Tetrapeptide-3 work?

Acetyl Tetrapeptide-3 is a synthetic four-amino-acid peptide that is a key component of the trademarked Capixyl complex. It works by stimulating extracellular matrix proteins in the scalp, increasing type III collagen expression by up to 65% and laminin expression by up to 285%, which strengthens the hair follicle anchoring environment. It also inhibits 5-alpha-reductase, the enzyme responsible for converting testosterone to DHT, a key driver of androgenetic hair loss.

Which products contain Acetyl Tetrapeptide-3?

Shop products that contain Acetyl Tetrapeptide-3