Researched by Helena DeMaria-Williams
Formula IngredientPeptideAcetyl Tetrapeptide-5
INCI: Acetyl Tetrapeptide-5
Acetyl Tetrapeptide-5, marketed under the trade name Eyeseryl, is a synthetic four-amino-acid peptide created through acetylation of tetrapeptide-5. It functions as both a cell-communicating ingredient and a humectant. It is designed to reduce under-eye puffiness through anti-oedema and anti-glycation mechanisms, targeting water accumulation that causes puffy eye bags. A manufacturer study of 20 volunteers using 10% Eyeseryl showed 70% improvement by day 15 and 95% by day 60.
Category
Peptide
Irritation Risk
Low
Skin Types
puffy eyes, under-eye bags, water retention around eyes, all skin types
What does this do in a formula?
anti-puffiness, anti-oedema, anti-glycation, under-eye bag reduction, moisturisation, eye area rejuvenation
Is Acetyl Tetrapeptide-5 safe? Key considerations
Can Acetyl Tetrapeptide-5 cause irritation?
Low RiskWell tolerated at cosmetic concentrations. No EU CosIng Annex II or III restrictions apply. Designed for use around the delicate eye area.
Does Acetyl Tetrapeptide-5 increase sun sensitivity?
No RiskAcetyl Tetrapeptide-5 does not increase photosensitivity.
Is Acetyl Tetrapeptide-5 safe during pregnancy?
CautionMANUAL REVIEW: Limited data on topical peptide safety during pregnancy. Systemic absorption is expected to be minimal, but no specific pregnancy safety studies are available. Consult a healthcare provider.
How does Acetyl Tetrapeptide-5 work?
Acetyl Tetrapeptide-5, marketed under the trade name Eyeseryl, is a synthetic four-amino-acid peptide created through acetylation of tetrapeptide-5. It functions as both a cell-communicating ingredient and a humectant. It is designed to reduce under-eye puffiness through anti-oedema and anti-glycation mechanisms, targeting water accumulation that causes puffy eye bags. A manufacturer study of 20 volunteers using 10% Eyeseryl showed 70% improvement by day 15 and 95% by day 60.
Which products contain Acetyl Tetrapeptide-5?
Shop products that contain Acetyl Tetrapeptide-5
