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Researched by Helena DeMaria-Williams

Formula IngredientSkin Conditioning

Allantoin

INCI: Allantoin

Allantoin is a naturally occurring compound found in comfrey root (Symphytum officinale), though the cosmetic-grade ingredient is typically produced synthetically for purity and consistency. It works by softening and loosening the outer layers of dead skin cells (keratolytic action), promoting gentle cell renewal without the irritation associated with chemical exfoliants. It also has well-documented soothing and wound-healing properties, making it a staple in sensitive skin and post-treatment formulations.

Category

Skin Conditioning

Irritation Risk

Low

Skin Types

all skin types, sensitive, dry, acne-prone, post-procedure, irritated or compromised skin

What does this do in a formula?

soothing, skin softening, wound healing support, gentle exfoliation, skin barrier protection, calming redness and irritation

Is Allantoin safe? Key considerations

Can Allantoin cause irritation?

Low Risk

Allantoin has an irritancy rating of 0 — it is one of the most well-tolerated cosmetic ingredients across all skin types. No EU CosIng Annex II or III restrictions apply. It is frequently used specifically to counteract irritation caused by other active ingredients in formulations.

Does Allantoin increase sun sensitivity?

No Risk

Allantoin does not increase photosensitivity. No sun protection precautions are required based on its presence in a formulation.

Is Allantoin safe during pregnancy?

Safe

Allantoin is widely considered safe for use during pregnancy at typical cosmetic concentrations (0.1–2%). It has no known reproductive or developmental toxicity concerns and is commonly found in pregnancy skincare products.

How does Allantoin work?

Allantoin is a naturally occurring compound found in comfrey root (Symphytum officinale), though the cosmetic-grade ingredient is typically produced synthetically for purity and consistency. It works by softening and loosening the outer layers of dead skin cells (keratolytic action), promoting gentle cell renewal without the irritation associated with chemical exfoliants. It also has well-documented soothing and wound-healing properties, making it a staple in sensitive skin and post-treatment formulations.