The Skin Formulary
IngredientsBrandsJournalShop
Browse Products

Researched by Helena DeMaria-Williams

Formula IngredientPeptide

Biotinoyl Tripeptide-1

INCI: Biotinoyl Tripeptide-1

Biotinoyl Tripeptide-1 is a synthetic peptide that combines biotin (vitamin B7) with Tripeptide-1 (GHK), a collagen fragment known for its cell-communicating properties. It is primarily used in hair and lash growth products, where it promotes keratinocyte proliferation in the hair bulb and strengthens hair anchorage by stimulating adhesion molecules such as laminin 5 and collagen IV.

Category

Peptide

Irritation Risk

Low

Skin Types

thinning hair, sparse lashes, lash growth, hair strengthening, all skin types

What does this do in a formula?

hair loss reduction, lash growth, lash thickness, hair anchorage strengthening, keratinocyte proliferation

Is Biotinoyl Tripeptide-1 safe? Key considerations

Can Biotinoyl Tripeptide-1 cause irritation?

Low Risk

Well tolerated at cosmetic concentrations. No EU CosIng Annex II or III restrictions apply. No significant irritation reported in clinical studies at 2% concentration.

Does Biotinoyl Tripeptide-1 increase sun sensitivity?

No Risk

Biotinoyl Tripeptide-1 does not increase photosensitivity. No additional sun protection is required.

Is Biotinoyl Tripeptide-1 safe during pregnancy?

Caution

MANUAL REVIEW: Limited data on topical peptide safety during pregnancy. Systemic absorption is expected to be minimal, but no specific pregnancy safety studies are available. Consult a healthcare provider.

How does Biotinoyl Tripeptide-1 work?

Biotinoyl Tripeptide-1 is a synthetic peptide that combines biotin (vitamin B7) with Tripeptide-1 (GHK), a collagen fragment known for its cell-communicating properties. It is primarily used in hair and lash growth products, where it promotes keratinocyte proliferation in the hair bulb and strengthens hair anchorage by stimulating adhesion molecules such as laminin 5 and collagen IV.

Which products contain Biotinoyl Tripeptide-1?

Shop products that contain Biotinoyl Tripeptide-1