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Researched by Helena DeMaria-Williams

Formula IngredientCeramide

Ceramide AP

INCI: Ceramide AP

Ceramide AP (formerly Ceramide 6 II, EC 309-560-3) is a naturally occurring sphingolipid found in the skin's stratum corneum. It consists of phytosphingosine with the d-erythro structure linked to an alpha-hydroxy saturated or unsaturated fatty acid, distinguishing it from other ceramides by its alpha-hydroxy fatty acid chain. Ceramides collectively make up approximately 50% of the intercellular lipid matrix and are essential for maintaining a healthy skin barrier and preventing transepidermal water loss.

Category

Ceramide

Irritation Risk

Low

Skin Types

dry, sensitive, compromised, eczema-prone, psoriasis-prone, mature skin, all skin types

What does this do in a formula?

skin barrier repair, moisture retention, reduction of transepidermal water loss, soothing dry and compromised skin, supporting healthy skin barrier function

Is Ceramide AP safe? Key considerations

Can Ceramide AP cause irritation?

Low Risk

Ceramide AP is a skin-identical ingredient with no known irritation risk. It is well tolerated by sensitive skin, including those with eczema, psoriasis, and dermatitis. No EU CosIng Annex II or III restrictions apply.

Does Ceramide AP increase sun sensitivity?

No Risk

Ceramide AP does not increase photosensitivity. No sun protection precautions are required based on its presence in a formulation.

Is Ceramide AP safe during pregnancy?

Safe

Ceramide AP is a skin-identical lipid naturally present in human skin. It has no known systemic absorption concerns and is widely considered safe during pregnancy and breastfeeding. No contraindications have been identified in available safety data.

How does Ceramide AP work?

Ceramide AP (formerly Ceramide 6 II, EC 309-560-3) is a naturally occurring sphingolipid found in the skin's stratum corneum. It consists of phytosphingosine with the d-erythro structure linked to an alpha-hydroxy saturated or unsaturated fatty acid, distinguishing it from other ceramides by its alpha-hydroxy fatty acid chain. Ceramides collectively make up approximately 50% of the intercellular lipid matrix and are essential for maintaining a healthy skin barrier and preventing transepidermal water loss.

Individuals with known allergy to ceramide-derived ingredients (very rare) should review the considerations above before use.

Which products contain Ceramide AP?

Shop products that contain Ceramide AP