Researched by Helena DeMaria-Williams
Formula IngredientCeramideINCI: Ceramide NP
Ceramide NP (also known as Ceramide 3) is a naturally occurring sphingolipid found in the skin's stratum corneum, where ceramides collectively make up approximately 50% of the intercellular lipid matrix. It is an N-acylated sphingolipid consisting of phytosphingosine linked to a normal saturated or unsaturated fatty acid, and plays a critical role in maintaining skin barrier integrity and regulating water loss.
Category
Ceramide
Irritation Risk
Low
Skin Types
dry, sensitive, compromised, eczema-prone, psoriasis-prone, mature skin, all skin types
skin barrier repair, moisture retention, reduction of transepidermal water loss, soothing dry and compromised skin, supporting healthy skin microbiome balance
Ceramide NP is a skin-identical ingredient with no known irritation risk. It is well tolerated by sensitive skin, including those with eczema, psoriasis, and dermatitis. No EU Annex restrictions apply.
Ceramide NP does not increase photosensitivity. No sun protection precautions specific to ceramide NP are required.
Ceramide NP is a skin-identical lipid naturally present in human skin. It has no known systemic absorption concerns and is widely considered safe during pregnancy and breastfeeding. No contraindications identified across reviewed sources.
Ceramide NP (also known as Ceramide 3) is a naturally occurring sphingolipid found in the skin's stratum corneum, where ceramides collectively make up approximately 50% of the intercellular lipid matrix. It is an N-acylated sphingolipid consisting of phytosphingosine linked to a normal saturated or unsaturated fatty acid, and plays a critical role in maintaining skin barrier integrity and regulating water loss.
Individuals with known allergy to ceramide-derived ingredients (very rare) should review the considerations above before use.
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