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Researched by Helena DeMaria-Williams

Formula IngredientCeramide

Ceramide NP

INCI: Ceramide NP

Ceramide NP (also known as Ceramide 3) is a naturally occurring sphingolipid found in the skin's stratum corneum, where ceramides collectively make up approximately 50% of the intercellular lipid matrix. It is an N-acylated sphingolipid consisting of phytosphingosine linked to a normal saturated or unsaturated fatty acid, and plays a critical role in maintaining skin barrier integrity and regulating water loss.

Category

Ceramide

Irritation Risk

Low

Skin Types

dry, sensitive, compromised, eczema-prone, psoriasis-prone, mature skin, all skin types

What does this do in a formula?

skin barrier repair, moisture retention, reduction of transepidermal water loss, soothing dry and compromised skin, supporting healthy skin microbiome balance

Is Ceramide NP safe? Key considerations

Can Ceramide NP cause irritation?

Low Risk

Ceramide NP is a skin-identical ingredient with no known irritation risk. It is well tolerated by sensitive skin, including those with eczema, psoriasis, and dermatitis. No EU Annex restrictions apply.

Does Ceramide NP increase sun sensitivity?

No Risk

Ceramide NP does not increase photosensitivity. No sun protection precautions specific to ceramide NP are required.

Is Ceramide NP safe during pregnancy?

Safe

Ceramide NP is a skin-identical lipid naturally present in human skin. It has no known systemic absorption concerns and is widely considered safe during pregnancy and breastfeeding. No contraindications identified across reviewed sources.

How does Ceramide NP work?

Ceramide NP (also known as Ceramide 3) is a naturally occurring sphingolipid found in the skin's stratum corneum, where ceramides collectively make up approximately 50% of the intercellular lipid matrix. It is an N-acylated sphingolipid consisting of phytosphingosine linked to a normal saturated or unsaturated fatty acid, and plays a critical role in maintaining skin barrier integrity and regulating water loss.

Individuals with known allergy to ceramide-derived ingredients (very rare) should review the considerations above before use.