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Researched by Helena DeMaria-Williams

Formula IngredientPolysaccharide / Hydrating Agent

Dextran

INCI: Dextran

Dextran is a naturally derived polysaccharide composed of glucose units linked through α-C1-C6 chains, produced by bacterial fermentation using species such as Leuconostoc and Streptococcus. In cosmetics it primarily functions as a viscosity controller and binder, helping to thicken and stabilise formulations. It also demonstrates humectant-like water-retention properties, supports the delivery of co-applied active ingredients, and has been shown to stimulate cell growth and boost tissue regeneration.

Category

Polysaccharide / Hydrating Agent

Irritation Risk

Low

Skin Types

all skin types, sensitive skin, dry skin, mature skin, acne-prone skin

What does this do in a formula?

water retention, viscosity control, formulation stabilisation, penetration enhancement, cell stimulation, tissue regeneration support, skin microbiota balance

Is Dextran safe? Key considerations

Can Dextran cause irritation?

Low Risk

Dextran has proven biocompatibility and is not listed under EU CosIng Annex II (prohibited) or Annex III (restricted substances). It is present in only 0.2% of surveyed cosmetics and is well tolerated across product types including eye-area formulations such as mascaras and lash serums. No known sensitisation or irritancy concerns have been identified at cosmetic-use concentrations.

Does Dextran increase sun sensitivity?

No Risk

Dextran does not increase photosensitivity. No sun protection precautions are associated with its use.

Is Dextran safe during pregnancy?

Safe

Dextran is a high-molecular-weight polysaccharide with negligible dermal absorption. No reproductive or developmental concerns are noted in available safety databases. It is considered low risk for topical use during pregnancy, though formal clinical data in pregnant populations are limited.

How does Dextran work?

Dextran is a naturally derived polysaccharide composed of glucose units linked through α-C1-C6 chains, produced by bacterial fermentation using species such as Leuconostoc and Streptococcus. In cosmetics it primarily functions as a viscosity controller and binder, helping to thicken and stabilise formulations. It also demonstrates humectant-like water-retention properties, supports the delivery of co-applied active ingredients, and has been shown to stimulate cell growth and boost tissue regeneration.