Researched by Helena DeMaria-Williams
Formula IngredientAntioxidantDimethylmethoxy Chromanol
INCI: Dimethylmethoxy Chromanol
Dimethylmethoxy Chromanol (also known as Lipochroman-6) is a synthetic chromanol derivative structurally similar to vitamin E. It is a potent antioxidant uniquely capable of protecting against both reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are major contributors to premature skin ageing and cellular damage from UV exposure and pollution.
Category
Antioxidant
Irritation Risk
Low
Skin Types
all skin types, sensitive, oily, dry, combination, acne-prone, mature skin, anti-ageing concerns
What does this do in a formula?
antioxidant protection, neutralisation of reactive oxygen and nitrogen species, anti-ageing, cellular protection, skin brightening
Is Dimethylmethoxy Chromanol safe? Key considerations
Can Dimethylmethoxy Chromanol cause irritation?
Low RiskWell tolerated at recommended cosmetic concentrations (0.01–0.05%). No EU CosIng Annex II or III restrictions apply. Products containing this ingredient are commonly formulated for sensitive areas including the eye contour, suggesting a favourable irritation profile.
Does Dimethylmethoxy Chromanol increase sun sensitivity?
No RiskDimethylmethoxy Chromanol does not increase photosensitivity. As an antioxidant, it provides indirect photoprotective benefits by neutralising UV-generated free radicals, but it is not a UV filter.
Is Dimethylmethoxy Chromanol safe during pregnancy?
CautionMANUAL REVIEW: No dedicated pregnancy safety assessment for dimethylmethoxy chromanol was found in EWG Skin Deep, MotherToBaby, or CIR databases. It is used at very low concentrations (0.01–0.05%) which limits systemic exposure. Until formal assessment is available, a precautionary Caution rating is applied. Consult a healthcare provider if concerned.
How does Dimethylmethoxy Chromanol work?
Dimethylmethoxy Chromanol (also known as Lipochroman-6) is a synthetic chromanol derivative structurally similar to vitamin E. It is a potent antioxidant uniquely capable of protecting against both reactive oxygen species (ROS) and reactive nitrogen species (RNS), which are major contributors to premature skin ageing and cellular damage from UV exposure and pollution.
Which products contain Dimethylmethoxy Chromanol?
Shop products that contain Dimethylmethoxy Chromanol
