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Researched by Helena DeMaria-Williams

Formula IngredientAmino Acid

Glycine

INCI: Glycine

Glycine is the simplest and smallest amino acid, naturally present in the skin as part of the Natural Moisturising Factor (NMF). It is a key building block of collagen (making up roughly one-third of collagen's amino acid composition) and elastin. In cosmetics it functions as a moisturiser and skin-conditioning agent, and research suggests it may support wound healing and tissue repair.

Category

Amino Acid

Irritation Risk

Low

Skin Types

all skin types, dry, dehydrated, sensitive, mature, wound-prone skin

What does this do in a formula?

hydration, skin conditioning, collagen support, wound healing support, anti-wrinkle (in combination with leucine and proline), skin-identical moisturisation

Is Glycine safe? Key considerations

Can Glycine cause irritation?

Low Risk

As the simplest naturally occurring amino acid and a major component of the skin's own proteins, glycine is extremely well tolerated. No irritation concerns at cosmetic concentrations. Not subject to any EU Annex restrictions.

Does Glycine increase sun sensitivity?

No Risk

Glycine does not increase photosensitivity. No UV-related precautions are required.

Is Glycine safe during pregnancy?

Safe

Glycine is a naturally occurring amino acid abundant in the body and in food. It is considered safe for topical cosmetic use during pregnancy.

How does Glycine work?

Glycine is the simplest and smallest amino acid, naturally present in the skin as part of the Natural Moisturising Factor (NMF). It is a key building block of collagen (making up roughly one-third of collagen's amino acid composition) and elastin. In cosmetics it functions as a moisturiser and skin-conditioning agent, and research suggests it may support wound healing and tissue repair.