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Researched by Helena DeMaria-Williams

Formula IngredientPeptide

Heptapeptide-6

INCI: Heptapeptide-6

Heptapeptide-6 is a synthetic peptide composed of seven amino acids: asparagine, aspartic acid, glutamic acid, glycine, leucine, and tyrosine. It functions as a skin-conditioning ingredient in anti-ageing formulations, where it is used to support skin firmness and smoothness through cell-communicating peptide signalling.

Category

Peptide

Irritation Risk

Low

Skin Types

all skin types, mature, anti-ageing concerns

What does this do in a formula?

skin conditioning, anti-ageing, skin firmness support, smoothing

Is Heptapeptide-6 safe? Key considerations

Can Heptapeptide-6 cause irritation?

Low Risk

Heptapeptide-6 is used at very low concentrations in cosmetic formulations and is not considered irritating. Synthetic peptides are generally well tolerated. No EU CosIng Annex II or III restrictions apply.

Does Heptapeptide-6 increase sun sensitivity?

No Risk

Heptapeptide-6 does not increase photosensitivity. No special sun protection measures are required beyond a standard daily SPF routine.

Is Heptapeptide-6 safe during pregnancy?

Caution

MANUAL REVIEW: No specific pregnancy safety data exists for topical heptapeptide-6 in MotherToBaby, EWG, or major toxicological databases. As a synthetic peptide used at very low concentrations with minimal systemic absorption, it is unlikely to pose significant risk, but the absence of dedicated safety studies warrants caution.

How does Heptapeptide-6 work?

Heptapeptide-6 is a synthetic peptide composed of seven amino acids: asparagine, aspartic acid, glutamic acid, glycine, leucine, and tyrosine. It functions as a skin-conditioning ingredient in anti-ageing formulations, where it is used to support skin firmness and smoothness through cell-communicating peptide signalling.

Which products contain Heptapeptide-6?

Shop products that contain Heptapeptide-6