Researched by Helena DeMaria-Williams
Formula IngredientHumectantINCI: Hydrolyzed Hyaluronic Acid
Hydrolyzed hyaluronic acid is a low molecular weight form of hyaluronic acid that has been broken down through acid, enzyme, or other hydrolysis methods into smaller fragments. Because of its reduced molecular size (typically 10–300 kDa compared to 1,000+ kDa for standard HA), it penetrates the skin more effectively, delivering deep and long-lasting hydration to lower layers of the epidermis rather than sitting on the surface.
Category
Humectant
Irritation Risk
Low
Skin Types
all skin types, dry, dehydrated, sensitive, acne-prone, ageing skin
deep hydration, improved skin penetration, reduced fine lines and wrinkles, skin barrier support, skin repair, soothing for sensitive skin
Well tolerated by most skin types, including sensitive skin. Ultra-low molecular weight fragments (below 50 kDa) have been noted in some research to trigger pro-inflammatory signalling, but at typical cosmetic concentrations this is not considered a clinical concern for most users.
Hydrolyzed hyaluronic acid does not increase photosensitivity. No special UV precautions are required.
Hyaluronic acid and its hydrolysed forms are naturally occurring in the body and are considered safe for topical use during pregnancy. No concerns have been raised by dermatological or toxicological sources.
Hydrolyzed hyaluronic acid is a low molecular weight form of hyaluronic acid that has been broken down through acid, enzyme, or other hydrolysis methods into smaller fragments. Because of its reduced molecular size (typically 10–300 kDa compared to 1,000+ kDa for standard HA), it penetrates the skin more effectively, delivering deep and long-lasting hydration to lower layers of the epidermis rather than sitting on the surface.
Individuals with known allergy to hyaluronic acid (extremely rare) should review the considerations above before use.
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