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Researched by Helena DeMaria-Williams

Active IngredientSkin Brightening, Humectant, Cell-Communicating Ingredient

Niacinamide

INCI: Niacinamide

Niacinamide is a water-soluble form of vitamin B3 (nicotinamide) that is synthetically manufactured for cosmetic use. It works through multiple mechanisms: suppressing melanin transfer to skin cells to reduce hyperpigmentation, stimulating ceramide and fatty acid synthesis to strengthen the skin barrier, regulating sebum production, and exerting anti-inflammatory effects. It is one of the most well-researched and versatile active ingredients in skincare.

Typical Concentration

2–5%for barrier repair, brightening and acne
4–5%for anti-ageing (used daily for 8–12 weeks)
up to 10%in some formulations
OTC concentrations typically 2–10%

Best For Skin Types

all skin typesoilyacne-pronehyperpigmentationrosaceasensitiveatopic dermatitisanti-ageing concerns

CAS Number

98-92-0

What are the benefits of Niacinamide?

brightening
hyperpigmentation reduction
barrier repair
sebum regulation
anti-acne
smoothing texture
anti-ageing
collagen support
redness reduction

Is Niacinamide safe? Key considerations

Can Niacinamide cause irritation?

Low Risk

Niacinamide is well-tolerated by most skin types, including sensitive skin. At very high concentrations (above 5%) some individuals may experience flushing or mild redness, particularly those with rosacea or reactive skin. This is distinct from niacin flush and is uncommon at typical cosmetic concentrations of 2–5%. No EU Annex restrictions apply.

Does Niacinamide increase sun sensitivity?

No Risk

Niacinamide does not increase photosensitivity. It is safe to use morning and evening without mandatory SPF requirement due to the ingredient itself, though daily SPF is always recommended for hyperpigmentation management.

Is Niacinamide safe during pregnancy?

Safe

Niacinamide is a B vitamin with a well-established safety profile. It is widely considered safe for use during pregnancy at cosmetic concentrations (2–10%). No known teratogenic effects at topical use levels. Consult a healthcare provider if in doubt.

How does Niacinamide work?

Niacinamide is a skin brightening, humectant, cell-communicating ingredient active used across a range of concentrations depending on the application and product format.

Particularly beneficial for all skin types and oily and acne-prone and hyperpigmentation and rosacea and sensitive and atopic dermatitis and anti-ageing concerns skin.

Individuals with known hypersensitivity to niacinamide or nicotinamide; use with caution at concentrations above 5% on highly reactive or rosacea-prone skin should review the considerations above before use.

How do you use Niacinamide in your routine?

A step-by-step guide to introducing Niacinamide into your skincare routine safely and effectively.

01

Choose the right concentration

Start with a product containing 2–5% for barrier repair, brightening and acne. Lower concentrations are better for beginners or sensitive skin.

02

Introduce gradually

Niacinamide is generally well tolerated. Start by applying once daily and adjust based on how your skin responds.

03

Apply morning or evening

Niacinamide does not increase sun sensitivity, so it can be used in either your morning or evening routine.

04

Follow with moisturiser

After Niacinamide has absorbed, apply a moisturiser to support your skin barrier. This is especially important when using active ingredients.

Science & Research

Research references for this ingredient are coming soon.