Researched by Helena DeMaria-Williams
Formula IngredientHumectantPentylene Glycol
INCI: Pentylene Glycol
Pentylene glycol (INCI: Pentylene Glycol, CAS 5343-92-0) is a synthetic short-chain diol (1,2-dihydroxypentane) used in cosmetics as a multifunctional humectant and solvent. It draws moisture into the skin while also functioning as a broad-spectrum antimicrobial agent that boosts the efficacy of other preservatives, allowing formulators to use lower concentrations of traditional preservatives. It additionally improves product texture and enhances the water-resistance of sunscreen formulations.
Category
Humectant
Irritation Risk
Low
Skin Types
all skin types, oily, acne-prone, combination, dry, sensitive (patch test recommended)
What does this do in a formula?
moisturisation, humectancy, antimicrobial preservation, solvent, emulsion stabilisation, improved skin feel, preservative boosting
Is Pentylene Glycol safe? Key considerations
Can Pentylene Glycol cause irritation?
Low RiskGenerally rated low hazard. However, documented cases of contact dermatitis have been reported, particularly in individuals sensitive to glycols — it is structurally related to propylene glycol (a known allergen) but is considered less irritating. Patch testing is recommended for those with known glycol sensitivity or reactive skin. No EU CosIng Annex II or III restrictions apply.
Does Pentylene Glycol increase sun sensitivity?
No RiskPentylene glycol has no known photosensitising mechanism. No special sun protection precautions are required based solely on its presence in a formulation.
Is Pentylene Glycol safe during pregnancy?
SafePentylene glycol has no known reproductive or developmental toxicity concerns. It is not listed under EU Annex II (banned) or Annex III (restricted) substances. No specific pregnancy warnings appear in available cosmetic safety databases. General precaution of avoiding high-concentration leave-on products applies as with all cosmetic glycols.
How does Pentylene Glycol work?
Pentylene glycol (INCI: Pentylene Glycol, CAS 5343-92-0) is a synthetic short-chain diol (1,2-dihydroxypentane) used in cosmetics as a multifunctional humectant and solvent. It draws moisture into the skin while also functioning as a broad-spectrum antimicrobial agent that boosts the efficacy of other preservatives, allowing formulators to use lower concentrations of traditional preservatives. It additionally improves product texture and enhances the water-resistance of sunscreen formulations.
Individuals with known glycol allergy or sensitivity, contact dermatitis history with propylene glycol should review the considerations above before use.
Which products contain Pentylene Glycol?
Shop products that contain Pentylene Glycol
Advanced 0.2% Retinal Serum
Exosome Glow Serum
Ectoin Hydro-Barrier Serum
Milk Cleanser
Hydrating Face Mist
Biome Balancing Moisturiser
Blemish Clearing Moisturiser with 2% Novoretin
PHA Toner
Hyaluronic Acid 2% + B5 (with Ceramides)
Multi-Peptide + Copper Peptides 1% Serum
Niacinamide 10% + Zinc 1%
Caffeine Solution 5% + EGCG Eye Serum
Natural Moisturizing Factors + HA
UV Filters SPF 45 Serum
Natural Moisturizing Factors + PhytoCeramides
Glycolipid Cream Cleanser
Multi-Peptide Eye Serum
Multi-Peptide + HA Serum
Natural Moisturizing Factors + Beta Glucan
AHA 30% + BHA 2% Peeling Solution
Salicylic Acid 2% Anhydrous Solution
Soothing & Barrier Support Serum
Natural Moisturizing Factors + Inulin Body Lotion
Niacinamide 5% Face and Body Emulsion
Salicylic Acid 2% Masque
Balancing & Clarifying Serum
Lactic Acid 5% + HA
Lactic Acid 10% + HA
Aloe 2% + NAG 2% Solution
Mandelic Acid 10% + HA
Hyaluronic Acid 2% + B5 (Original Formulation)
