Researched by Helena DeMaria-Williams
Formula IngredientAmino AcidPhenylalanine
INCI: Phenylalanine
Phenylalanine is an essential amino acid that the human body cannot synthesise and must obtain from external sources. In skincare, it is classified as a skin-identical ingredient that supports the skin's natural moisturising factor (NMF). It has also been studied in combination with UVA exposure for the treatment of vitiligo.
Category
Amino Acid
Irritation Risk
Low
Skin Types
all skin types, dry skin, dehydrated skin, sensitive skin
What does this do in a formula?
skin conditioning, moisturisation, skin-identical hydration, supports natural moisturising factor
Is Phenylalanine safe? Key considerations
Can Phenylalanine cause irritation?
Low RiskPhenylalanine has an excellent safety profile with a CIR rating of A and an EWG hazard score of 1. No irritation concerns have been documented at cosmetic-use concentrations. No EU CosIng Annex II or III restrictions apply.
Does Phenylalanine increase sun sensitivity?
No RiskPhenylalanine does not increase photosensitivity. Note: when used therapeutically for vitiligo treatment, it is combined with UVA exposure, but this is a medical application and not a concern in standard cosmetic use.
Is Phenylalanine safe during pregnancy?
SafePhenylalanine is a naturally occurring essential amino acid present in the human body. No documented reproductive or developmental concerns for topical cosmetic use. Individuals with phenylketonuria (PKU) should consult a healthcare provider, though topical absorption is minimal.
How does Phenylalanine work?
Phenylalanine is an essential amino acid that the human body cannot synthesise and must obtain from external sources. In skincare, it is classified as a skin-identical ingredient that supports the skin's natural moisturising factor (NMF). It has also been studied in combination with UVA exposure for the treatment of vitiligo.
Which products contain Phenylalanine?
Shop products that contain Phenylalanine
Glycolic Acid 7% Exfoliating Toner
Multi-Peptide + Copper Peptides 1% Serum
Natural Moisturizing Factors + HA
Multi-Peptide + HA Serum
Marine Hyaluronics
