Researched by Helena DeMaria-Williams
Formula IngredientRetinoidINCI: Retinol
Retinol is a form of vitamin A and one of the most well-researched anti-ageing skincare ingredients. It is a cell-communicating ingredient that must be converted in the skin through two enzymatic steps (retinol → retinaldehyde → retinoic acid) before it becomes biologically active. It is approximately 10–20 times less potent than prescription tretinoin, making it more tolerable for OTC use.
Category
Retinoid
Irritation Risk
Medium
Skin Types
oily, acne-prone, anti-ageing concerns, hyperpigmentation, dull skin, uneven texture
anti-ageing, wrinkle reduction, collagen stimulation, skin firming, cell turnover, brightening, smoothing texture, acne treatment, pore minimising, fading hyperpigmentation
Retinol is significantly better tolerated than prescription retinoic acid but can still cause initial redness, dryness, flaking, and sensitivity — especially at concentrations above 0.5% or when first introduced. Beginners should start with 0.1–0.25% applied 2–3 times per week and build up gradually. The 'sandwich method' (applying between moisturiser layers) can reduce irritation.
Retinol increases photosensitivity and should be used as part of a PM routine only. Daily SPF 30+ is strongly recommended during treatment, as the skin is more vulnerable to UV-induced damage while using retinoids.
All topical retinoids, including retinol, are advised to be avoided during pregnancy and breastfeeding. While systemic absorption from topical OTC retinol is low, the teratogenic risk associated with the retinoid class means avoidance is the standard clinical recommendation. Consult a healthcare provider.
Retinol is a form of vitamin A and one of the most well-researched anti-ageing skincare ingredients. It is a cell-communicating ingredient that must be converted in the skin through two enzymatic steps (retinol → retinaldehyde → retinoic acid) before it becomes biologically active. It is approximately 10–20 times less potent than prescription tretinoin, making it more tolerable for OTC use.
Individuals with pregnancy, breastfeeding, sensitive skin (without medical guidance), rosacea, eczema, active sunburn, open wounds should review the considerations above before use.
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