Researched by Helena DeMaria-Williams
Formula IngredientBuffering AgentINCI: Tromethamine
Tromethamine (also known as Tris or THAM) is a synthetic organic compound with an alkaline pH used in cosmetic formulations as a buffering agent. It works by neutralising acidic ingredients and stabilising the pH of a product to ensure it remains within the optimal range for skin compatibility and ingredient efficacy. It also serves a masking function, reducing the perceptible odour of certain raw materials.
Category
Buffering Agent
Irritation Risk
Low
Skin Types
all skin types, oily, dry, combination, sensitive, acne-prone
pH stabilisation, formulation buffering, ingredient compatibility, neutralisation of acidic actives
Tromethamine is considered non-irritating at the concentrations used in cosmetic formulations. It is a functional ingredient present at low levels primarily to stabilise pH rather than to act on the skin directly. EU CosIng lists it under Annex III/61, which restricts its use in oxidative hair colouring products — this restriction does not apply to general skincare leave-on or rinse-off products.
Tromethamine does not increase photosensitivity. No sun protection precautions are required based on its presence in a formulation.
Tromethamine is used at very low concentrations as a pH adjuster and is not known to pose reproductive or developmental risks in topical cosmetic use. No specific pregnancy contraindications are noted in available safety databases for topical application.
Tromethamine (also known as Tris or THAM) is a synthetic organic compound with an alkaline pH used in cosmetic formulations as a buffering agent. It works by neutralising acidic ingredients and stabilising the pH of a product to ensure it remains within the optimal range for skin compatibility and ingredient efficacy. It also serves a masking function, reducing the perceptible odour of certain raw materials.
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