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Researched by Helena DeMaria-Williams

Formula IngredientAbsorbent, Chelating Agent

Cyclodextrin

INCI: Cyclodextrin

Cyclodextrin is a ring-shaped carbohydrate (cyclic oligosaccharide) derived from natural starch (typically corn or potato) through enzymatic breakdown. Its distinctive donut-shaped structure has a hydrophilic outer surface and a lipophilic hollow inner cavity, allowing it to encapsulate other molecules — trapping actives, fragrances, or oils without altering their structure. In cosmetics it functions as both an absorbent (reducing excess oil and sweat) and a chelating agent (binding metal ions that can destabilise formulations or trigger irritation).

Category

Absorbent, Chelating Agent

Irritation Risk

Low

Skin Types

all skin types, particularly oily, combination, acne-prone

What does this do in a formula?

sebum absorption, mattifying, oil control, formula stabilisation, chelating metal ions, controlled release of encapsulated actives, fragrance retention, improved solubility of poorly soluble compounds

Is Cyclodextrin safe? Key considerations

Can Cyclodextrin cause irritation?

Low Risk

Generally considered non-irritating at typical cosmetic use concentrations (0.1–5%). Rare cases of mild irritation or temporary tightness have been reported in very sensitive skin. Individuals with known corn or potato starch sensitivities should patch test. No EU Annex II or III restrictions apply to cyclodextrin.

Does Cyclodextrin increase sun sensitivity?

No Risk

Cyclodextrin does not increase photosensitivity. No sun protection precautions are required specifically for this ingredient, though SPF is always recommended as part of a daytime routine.

Is Cyclodextrin safe during pregnancy?

Safe

No known risks identified for topical use. Animal studies on oral administration at doses below 600 mg/kg showed non-toxic profiles. Topical absorption is minimal. Limited specific human pregnancy data exists, so consulting a healthcare provider is recommended as a precaution (source: Motherfigure/toxicity literature).

How does Cyclodextrin work?

Cyclodextrin is a ring-shaped carbohydrate (cyclic oligosaccharide) derived from natural starch (typically corn or potato) through enzymatic breakdown. Its distinctive donut-shaped structure has a hydrophilic outer surface and a lipophilic hollow inner cavity, allowing it to encapsulate other molecules — trapping actives, fragrances, or oils without altering their structure. In cosmetics it functions as both an absorbent (reducing excess oil and sweat) and a chelating agent (binding metal ions that can destabilise formulations or trigger irritation).

Individuals with known allergy to corn or potato starch derivatives (rare) should review the considerations above before use.