Researched by Helena DeMaria-Williams
Formula IngredientAntioxidant, Skin BrighteningDiglucosyl Gallic Acid
INCI: Diglucosyl Gallic Acid
Diglucosyl gallic acid (DGA) is a biotechnologically created derivative of gallic acid (a benzoic acid compound) in which two glucose molecules are attached to stabilise the active. Upon topical application, beneficial skin microbiota enzymatically convert it into trihydroxybenzoic acid (THBA), its active form. It works across multiple pathways to inhibit tyrosinase (the enzyme responsible for melanin production), neutralise free radicals, and reduce skin inflammation.
Category
Antioxidant, Skin Brightening
Irritation Risk
Low
Skin Types
all skin types, sensitive, oily, acne-prone, hyperpigmentation, uneven skin tone, dull skin, redness-prone
What does this do in a formula?
skin brightening, hyperpigmentation reduction, antioxidant protection, anti-inflammatory, redness reduction, UV-induced dark spot prevention, even skin tone
Is Diglucosyl Gallic Acid safe? Key considerations
Can Diglucosyl Gallic Acid cause irritation?
Low RiskClinical studies and multiple cosmetic ingredient sources indicate low irritation potential with good tolerability across skin types, including sensitive skin. No EU CosIng Annex II or III restrictions documented. Rare allergic sensitivities are possible; patch testing is recommended for reactive skin.
Does Diglucosyl Gallic Acid increase sun sensitivity?
No RiskDiglucosyl gallic acid does not increase photosensitivity. On the contrary, it has demonstrated photoprotective properties, helping to reduce UV-induced DNA damage, dark spots, and sun-induced discolouration when used alongside SPF. No additional sun protection precautions are required due to its presence.
Is Diglucosyl Gallic Acid safe during pregnancy?
MANUAL REVIEW: EWG rates it 1 (safest), and it is widely cited as pregnancy-safe topically, but no dedicated clinical pregnancy safety study was identified during research. Generally considered low risk based on its gallic acid (polyphenol) origin and topical use.EWG Skin Deep rates diglucosyl gallic acid a 1 (lowest hazard), and several skincare sources note it as suitable during pregnancy for addressing pregnancy-related hyperpigmentation. It is considered a gentle alternative to hydroquinone. No formal reproductive toxicology data was identified. Consult a healthcare provider if in doubt.
How does Diglucosyl Gallic Acid work?
Diglucosyl gallic acid (DGA) is a biotechnologically created derivative of gallic acid (a benzoic acid compound) in which two glucose molecules are attached to stabilise the active. Upon topical application, beneficial skin microbiota enzymatically convert it into trihydroxybenzoic acid (THBA), its active form. It works across multiple pathways to inhibit tyrosinase (the enzyme responsible for melanin production), neutralise free radicals, and reduce skin inflammation.
Individuals with known allergy to gallic acid derivatives (rare) should review the considerations above before use.
Which products contain Diglucosyl Gallic Acid?
Shop products that contain Diglucosyl Gallic Acid
