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Researched by Helena DeMaria-Williams

Formula IngredientDelivery System, Stabiliser

Hydroxypropyl Cyclodextrin

INCI: Hydroxypropyl Cyclodextrin

Hydroxypropyl cyclodextrin is a modified beta-cyclodextrin, a cyclic oligosaccharide composed of seven glucose units with a hydrophilic exterior and a lipophilic (oil-loving) interior cavity. This donut-shaped molecular structure allows it to encapsulate and stabilise other active ingredients, improving their solubility, bioavailability, and controlled release in cosmetic formulations.

Category

Delivery System, Stabiliser

Irritation Risk

Low

Skin Types

all skin types, sensitive, oily, dry, combination

What does this do in a formula?

active ingredient stabilisation, enhanced delivery of actives, improved solubility of lipophilic compounds, skin conditioning, fragrance stabilisation

Is Hydroxypropyl Cyclodextrin safe? Key considerations

Can Hydroxypropyl Cyclodextrin cause irritation?

Low Risk

Hydroxypropyl cyclodextrin has been reviewed as being of low toxicity and is well tolerated at typical cosmetic concentrations. No EU Annex II or III restrictions apply. It functions as a carrier rather than an active, so direct skin effects are minimal.

Does Hydroxypropyl Cyclodextrin increase sun sensitivity?

No Risk

Hydroxypropyl cyclodextrin does not increase photosensitivity.

Is Hydroxypropyl Cyclodextrin safe during pregnancy?

Safe

No known pregnancy concerns at cosmetic concentrations. The ingredient functions as an encapsulation agent and does not have systemic activity when applied topically.

How does Hydroxypropyl Cyclodextrin work?

Hydroxypropyl cyclodextrin is a modified beta-cyclodextrin, a cyclic oligosaccharide composed of seven glucose units with a hydrophilic exterior and a lipophilic (oil-loving) interior cavity. This donut-shaped molecular structure allows it to encapsulate and stabilise other active ingredients, improving their solubility, bioavailability, and controlled release in cosmetic formulations.