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Researched by Helena DeMaria-Williams

Formula IngredientEmollient, Humectant, Cell-Communicating Ingredient

Isosorbide Dicaprylate

INCI: Isosorbide Dicaprylate

Isosorbide Dicaprylate is the diester of isosorbide and caprylic acid, functioning as a multifunctional skin hydrator and barrier-strengthening molecule. It works synergistically with glycerin by upregulating Aquaporin 3 (AQP3), facilitating glycerin and water transport into skin cells, and may also upregulate CD44 (hyaluronic acid receptor) and ceramide synthase expression.

Category

Emollient, Humectant, Cell-Communicating Ingredient

Irritation Risk

Low

Skin Types

dry, very dry, dehydrated, sensitive, normal, combination, mature

What does this do in a formula?

deep hydration, skin barrier strengthening, reduces transepidermal water loss, synergistic with glycerin, ceramide synthesis support

Is Isosorbide Dicaprylate safe? Key considerations

Can Isosorbide Dicaprylate cause irritation?

Low Risk

Generally well tolerated at typical cosmetic concentrations. No EU CosIng Annex II or III restrictions apply. No significant irritation reports in available literature.

Does Isosorbide Dicaprylate increase sun sensitivity?

No Risk

Isosorbide dicaprylate does not increase photosensitivity. No sun protection precautions are required.

Is Isosorbide Dicaprylate safe during pregnancy?

Safe

No known pregnancy concerns. Functions as a topical emollient and humectant with no systemic activity reported.

How does Isosorbide Dicaprylate work?

Isosorbide Dicaprylate is the diester of isosorbide and caprylic acid, functioning as a multifunctional skin hydrator and barrier-strengthening molecule. It works synergistically with glycerin by upregulating Aquaporin 3 (AQP3), facilitating glycerin and water transport into skin cells, and may also upregulate CD44 (hyaluronic acid receptor) and ceramide synthase expression.

Which products contain Isosorbide Dicaprylate?

Shop products that contain Isosorbide Dicaprylate