The Skin Formulary
IngredientsBrandsJournalShop
Browse Products

Researched by Helena DeMaria-Williams

Formula IngredientEmollient

Squalane

INCI: Squalane

Squalane is a saturated hydrocarbon (C30H62) naturally found in human sebum and derived from plant sources such as sugarcane, olives, and amaranth seed. It functions as a highly effective emollient and skin-identical ingredient, mimicking the skin's own oils to soften and smooth the skin barrier without heaviness or greasiness.

Category

Emollient

Irritation Risk

Low

Skin Types

all skin types, dry, oily, combination, sensitive, acne-prone, fungal acne-prone, mature skin

What does this do in a formula?

deep moisturisation, barrier reinforcement, prevention of transepidermal water loss, skin softening, improved skin texture, antioxidant support

Is Squalane safe? Key considerations

Can Squalane cause irritation?

Low Risk

Squalane has an irritancy rating of 0 (INCIDecoder). It is exceptionally well tolerated across all skin types including sensitive and reactive skin. No EU Annex restrictions apply.

Does Squalane increase sun sensitivity?

No Risk

Squalane does not increase photosensitivity. No special sun protection precautions are required when using squalane.

Is Squalane safe during pregnancy?

Safe

Squalane is a skin-identical ingredient with no known systemic absorption concerns. It is widely considered safe for use during pregnancy and breastfeeding. No contraindications identified across reviewed sources.

How does Squalane work?

Squalane is a saturated hydrocarbon (C30H62) naturally found in human sebum and derived from plant sources such as sugarcane, olives, and amaranth seed. It functions as a highly effective emollient and skin-identical ingredient, mimicking the skin's own oils to soften and smooth the skin barrier without heaviness or greasiness.

Individuals with known allergy to squalane or squalene-derived sources (rare) should review the considerations above before use.

Which products contain Squalane?

Shop products that contain Squalane

Starter Retinol Serum

Starter Retinol Serum

Granactive Pro+: 1%Retinal: 0.01%
£12.00View →
Caffeine Eye Cream

Caffeine Eye Cream

Caffeine: 0.3%Matrixyl 3000
£10.00View →
Dewy Sunscreen SPF 30

Dewy Sunscreen SPF 30

Polyglutamic AcidGlycerin
£15.00View →
360° Skin Clearing Serum

360° Skin Clearing Serum

Dioic Acid: 1%Salicylic Acid: 2%
£16.00View →
10% Niacinamide Serum

10% Niacinamide Serum

Niacinamide: 10%Hyaluronic Acid
£10.00View →
Tripeptide Plumping Lip Balm

Tripeptide Plumping Lip Balm

Tripeptide Complex: 6%Ultra Filing Spheres: 2%
£11.00View →
1% Retinol Serum

1% Retinol Serum

Retinol: 1%Apricot Kernal Oil: 5%
£23.00View →
Retinol Serum

Retinol Serum

Retinyl Acetate:1%.granactive Retinoid:0.5%Squalane
£14.00View →
Succinic Acid Treatment

Succinic Acid Treatment

Succinic Acid: 2%Sulfur Powder: 2%
£11.00View →
Blemish Clearing Moisturiser with 2% Novoretin

Blemish Clearing Moisturiser with 2% Novoretin

Novoretin: 2%Stay C 50: 5%
£19.00View →
Tranexamic Acid Serum

Tranexamic Acid Serum

Tranexamic Acid: 2%Acai Berry Extract: 2%
£16.00View →
20% Niacinamide Serum

20% Niacinamide Serum

Niacinamide: 20%Zinc Pca: 0.5%
£16.00View →
10% Urea Moisturiser

10% Urea Moisturiser

Urea: 10%Collodial Oat: 1%
£19.00View →
Squalane + Amino Acids Lip Balm

Squalane + Amino Acids Lip Balm

SqualaneAmino acids
£8.50View →
Squalane Cleanser

Squalane Cleanser

SqualaneSucrose stearate
£14.90View →
Saccharomyces Ferment 30% Milky Toner

Saccharomyces Ferment 30% Milky Toner

Saccharomyces fermentSqualane
£12.40View →
Retinol 1% in Squalane

Retinol 1% in Squalane

RetinolSqualane
£9.00View →
Retinol 0.5% in Squalane

Retinol 0.5% in Squalane

RetinolSqualane
£8.40View →
Salicylic Acid 2% Anhydrous Solution

Salicylic Acid 2% Anhydrous Solution

Salicylic acid: 2%Squalane
£6.80View →
Retinol 0.2% in Squalane

Retinol 0.2% in Squalane

Retinol: 0.2%Squalane
£7.40View →
100% Plant-Derived Squalane

100% Plant-Derived Squalane

Squalane: 100%
£9.90View →
Granactive Retinoid 5% in Squalane

Granactive Retinoid 5% in Squalane

Hydroxypinacolone retinoateSqualane
£15.90View →
Vitamin C Suspension 23% + HA Spheres 2%

Vitamin C Suspension 23% + HA Spheres 2%

Ascorbic acidSodium hyaluronate
£7.70View →
Salicylic Acid 2% Masque

Salicylic Acid 2% Masque

Salicylic acid: 2%Kaolin
£25.10View →
Ascorbyl Tetraisopalmitate Solution 20% in Vitamin F

Ascorbyl Tetraisopalmitate Solution 20% in Vitamin F

Tetrahexyldecyl ascorbateEthyl linoleate
£19.50View →